Nucleosil CN, 100Å, 10µm, 4.0 x 250mm, ea.
Method: HPLC, analytical
Brand: NUCLEOSIL
Base material. NUCLEOSIL – the standard silica
Phase: NUCLEOSIL CN 100-10
Surface chemistry: Cyano, nitrile (CN) modification
Mode: Multi-mode (NP and RP), Normal phase (NP)
Type: EC HPLC column (analytical)
Hardware: Stainless steel
Column length: 250 mm
Column inner diameter: 4 mm
Particle type: Fully porous particles (FPP)
Particle shape: Spherical
Particle size: 10 µm
Eluent in HPLC column: n-heptane
Recommended application(s): HPLC, Organic acids, Reversed phase and normal phase chromatography, Steroids, Tricyclic antidepressants
Endcapped: No
Carbon content: 5.0 %
pH stability: 2.0–8.0
Pore size: 100 Å
Specific surface according to BET: 350 m²/g
Temperature stability (max): 60 °C
Pressure stability (max): 400 bar / 5800 psi
Column volume: 3.15 mL
Storage temperature: 15–25 °C / 59–77 °F
Scope of delivery: 1x analytical HPLC column, instruction leaflet, certificate of analysis
Gross weight (incl. packaging): 284 g / 0.63 lbs
Packaging dimensions: 115 x 400 x 50 mm / 4.53 x 15.75 x 1.97 Inch
Hazardous material: No
USP listing: L10
- Descripción
Descripción
SKU: 720024.40
The cyanopropyl phase is able to generate a clearly recognizable different retention behavior compared to purely alkyl-functionalized surface modifications. The polarity can be classified as intermediate based on multiple retention mechanisms such as dipole-dipole, π-π, and also hydrophobic interactions. Therefore, CN phases show a distinct selectivity for polar organic compounds as well as for molecules containing π-electron systems (e.g., analytes with double bonds). This HPLC phase can be run in the RP mode using aqueous-organic eluent mixtures as well as in the NP mode, e.g., with hexane as mobile phase. This HPLC column is packed with CN modification, based on the original NUCLEOSIL silica gel. It is one of the first spherical silicas for HPLC and was originally developed by MACHEREY-NAGEL in 1974. It is exclusively manufactured in Germany and is still one of the most used HPLC silicas in quality control around the globe.
